In an interview with abs-cbnNEWS.com, Santos said there's a big possibility for them to do a project together since they are under same network.
"Wala namang imposible. Pareho naman kaming nasa ABS-CBN, pareho kaming may kontrata sa Star Cinema, I think anything is possible," Santos told abs-cbnNEWS.com.
She revealed that she already told Star Cinema that she hopes to do a film with Cruz.
"Napag-usapan na namin yan. Tinanong na din naman ako if possible kung halimbawang magbabalik pelikula ako, sinagot ko 'si John Lloyd,'" she said.
"Of course, gusto kong maka-trabaho si John Lloyd eh baby boy ko 'yan. Nagkasama kami sa 'Puso Ko Ay Iingatan Ka' bilang kapatid ko. Naging close din kami ng sobra doon, tapos biglang nawala na lang hanggang sa ang sikat na sikat niya. Pero kapag nagkikita kami ay sobra naman ang pagbati niya," she added.
Santos said she's just proud that Cruz is able to keep his feet on the ground.
"Ito namang batang ito ay nakikita ko namang hindi naman siya nagbago," she said.
Currently, Cruz is promoting his newest film with Angel Locsin, "Unofficially Yours," which hit theaters today.
Based on the actor's box office record, he is already the all-time box office king based on the grosses of his previous films.
Six movies starring Cruz are on the list of all-time top local films shown in the Philippines, according to figures from Box Office Mojo -- more than any other actor. In fact, Cruz's films occupy the third to seventh spots on the list.
New indie film
Meanwhile, Santos also announced that she will be doing an independent film with actress Eugene Domingo.
"Gumagawa ako ng movie with direct Joey (Reyes) for Cinemalaya. First ko din 'yung pang-presko lang ba na gagawa ka ng isang character na out of the box. Nakakatuwa," Santos said.
The film, with the working title "Mga Mumunting Lihim," tells a story about friendship.
"Actually story siya ng mga magkakaibigan na....'yun lang ang pwede kong sabihin," she said.
"Ito ang istorya ng magkakaibigan and it applies to everyone, yung grupong kinalikihan mo na makaka-relate ang sinuman. Nabasa ko na siya at nakakatuwa kasi nakaka-excite magbitawan ng dialogue na di siya mase-censor kasi indie film siya. So exciting talaga," she said.
Aside from Domingo and Santos, Iza Calzado and Agot Isidro will also be part of the indie film.